We have developed specific CHW training programs in Pediatric Asthma, Pediatric Obesity and Adult Heart Failure. CHW’s trained at through the CUHE Training and Career Development Core work directly with the CURA 2 and CHART 2 project staff and research participants. The self-management intervention of CURA 2 is a series of home visits provided by Puerto Rican community health workers, focusing on an asthma core curriculum which is tailored to individual needs, strengths, and beliefs and targeting asthma triggers and adherence to therapy. CHART 2 aims to reduce repeated hospitalizations in low-income heart failure patients by improving doctor’s prescription of evidence-based medicine and patients’ adherence to these medicines with the use of CHW’s.